The COVID-19 pandemic created a unique “natural experiment” that highlighted how isolation, cultural influences, and social media exposure can converge to increase the risk of anorexia nervosa (AN) in vulnerable adolescents. Drawing on international evidence and research from Marmara University Child Psychiatry, this presentation demonstrates that pandemic-related disruptions—including loss of daily routines, reduced peer interaction, heightened anxiety, and increased screen time—were accompanied by a marked rise in eating disorders among young people. Rather than a single cause, AN emerges through the interaction of biological vulnerability, emotional distress, social isolation, appearance-focused social media, and cultural ideals that equate thinness with success, self-control, and social value. The presentation also examines how algorithms, social comparison, and “healthy lifestyle” content may reinforce body dissatisfaction and restrictive eating behaviors, particularly during adolescence, a critical period for identity development. Findings from Turkish clinical cohorts illustrate how these global mechanisms manifested locally, including a significant increase in new AN diagnoses during the pandemic and unique cultural pathways such as fasting during Ramadan evolving into persistent restrictive eating in susceptible individuals. Despite these risks, digital technology also offers opportunities for psychoeducation, social support, and early intervention when used responsibly. The presentation concludes by emphasizing protective factors—including strong family relationships, supportive peer networks, participation in performance-focused activities, media literacy, and timely mental health care—and discusses the future potential of digital phenotyping and ecological momentary assessment to identify adolescents on a high-risk trajectory before full clinical anorexia develops. Together, these findings underscore the importance of integrating biological, psychological, cultural, and digital perspectives in the prevention and early detection of adolescent eating disorders.Isolation culture and social media exposure Anorexia Nervosa IACAPAP 2026